One-stage Hybrid Operation Improves Safety In Treating Hypervascular Brain And Spinal Tumors

Hypervascular cardinal nervous system (CNS) tumors specified arsenic meningiomas, hemangioblastomas, and paragangliomas are known for their rich | humor supply, which tin obscure tumor boundaries and summation nan consequence of neurological wounded during surgery. Traditionally, these tumors are treated successful 2 stages: preoperative embolization to artifact humor flow, followed days later by tumor removal. While effective successful immoderate cases, this staged attack tin consequence successful complications, including swelling, hemorrhage, and delays betwixt treatments.

A investigation squad led by Professor Yi Lu, reviewed 31 cases treated betwixt 2014 and 2024. This insubstantial was published connected July 31, 2025, successful Volume 11, Article 14 successful Chinese Neurosurgical Journal. Patients ranged successful property from young adults to seniors, pinch tumors located successful challenging areas specified arsenic nan skull base, cerebellum, and brainstem. Gross-total tumor removal was achieved successful 71% of patients, pinch near-total removal successful 19.4% and partial removal successful 9.7%. The mean humor nonaccomplishment was 1,127 mL little than emblematic staged cases and nary embolization-related complications occurred. At discharge, 87% of patients had unchangeable aliases improved neurological function, and astatine 12 months, two-thirds were symptom-free. Professor Yi Lu explained, "There is an urgent request for an innovative solution that tin execute some vascular obliteration and elimination of complications".

The embolization strategy focused connected occluding heavy aliases surgically inaccessible arterial feeders, leaving superficial vessels to beryllium managed during surgery. This selective attack helped debar harm to normal encephalon vessels and reduced nan consequence of ischemic complications. Materials specified arsenic ethylene vinyl intoxicant copolymer (EVOH), detachable coils, and silk suture segments were utilized for targeted alloy closure, and successful definite cases, balloon catheters provided impermanent humor travel power during craniotomy. Unlike accepted preoperative embolization, nan purpose was not full alloy blockage, but strategical simplification of bleeding consequence during contiguous resection.

The one-stage hybrid method integrates some procedures into a azygous operation, performed successful a specialized hybrid operating room equipped for some endovascular and unfastened neurosurgery. This setup enables surgeons to artifact hard-to-reach tumor humor vessels and proceed straight to resection nether nan aforesaid anesthesia, reducing time, risk, and diligent stress.

"Our acquisition suggests that one-stage hybrid cognition is safe for nan curen of hypervascular CNS," said Professor Li. The researchers statement that while results are promising, larger prospective studies are needed to comparison this method straight pinch staged treatment. If validated, nan one-stage hybrid attack could go a caller modular for managing high-risk CNS tumors.

Source:

Journal reference:

Wang, M., et al. (2025). One-stage hybrid cognition for hypervascular cardinal tense strategy tumors: a single-center acquisition of 31 cases. Chinese Neurosurgical Journal. doi.org/10.1186/s41016-025-00400-y.