The American Geriatrics Society (AGS) has released a landmark update to its database of alternatives to medications listed successful nan 2023 AGS Beers Criteria® - nan astir wide adopted guidelines to thief clinicians place perchance inappropriate medications for older adults. This caller effort delivers not only a broad suite of safer pharmacologic options, but besides a beardown accent connected effective non-pharmacologic treatments for communal conditions impacting frail and aging populations.
The AGS sheet is comprised of 19 nationalist experts from 14 states, including Noll Campbell, PharmD, M.S., of nan Regenstrief Institute and Purdue University College of Pharmacy. Dr. Campbell is nan only master from Indiana. The sheet is simply a multidisciplinary AGS sheet of physicians, pharmacists, nurses, psychologists and beingness therapists that systematically reviewed and curated alternatives for immoderate of nan astir challenging prescribing scenarios faced successful geriatric practice.
The AGS Beers Criteria® identifies medications that are much apt to harm than thief older adults owed to broadside effects specified arsenic sedation, falls, delirium and interactions pinch different conditions. Recommendations are system for accelerated usage successful objective practice, emphasizing clear tables referenced by denotation aliases diagnosis and supplemented by links to reliable resources for some wellness professionals and nan public.
In practice, we spot nan risks of perchance inappropriate medications play retired successful nan emergency rooms, clinics, nursing homes aliases erstwhile families are struggling astatine home. Our purpose pinch this archive is to supply support beyond saying 'don't prescribe,' by offering clinicians, patients and families pinch a database of credible, actionable alternatives - whether it's a safer medicine aliases a proven manner approach."
Dr. Noll Campbell, PharmD, M.S., of nan Regenstrief Institute and Purdue University College of Pharmacy
A caller characteristic is nan inclusion of diligent and caregiver-friendly materials, from determination immunodeficiency and handouts connected deprescribing to support for making manner changes - reflecting a modern, team-based and patient-centered attack to medicine information for older adults. All of these resources are generated and hosted by nan American Geriatrics Society.
Rigorous, interprofessional approach
Panelists were assigned to 8 topic-specific workgroups covering insomnia and anxiety; allergy and pruritus (itchy skin); cardiovascular and anticoagulation therapies; pain; delirium and dementia; diabetes; gastrointestinal syndromes; and genitourinary syndromes.
Each group sought and reviewed high-quality guidelines, best-practice documents and systematic reviews astir applicable to communal geriatric scenarios. These resources were past distilled into tables of alternatives for 21 communal conditions. The sheet prioritized U.S.-based guidance but included world sources erstwhile much caller aliases rigorous. Notably, selections focused connected some medications and non-pharmacologic alternatives - specified arsenic cognitive behavioral therapy for insomnia, workout and beingness therapy for Parkinson's disease, manner changes for constipation and heartburn, and behavioral aliases dietary interventions for urinary symptoms.
Core principles for safer prescribing
To guideline clinicians, nan sheet offers 5 cardinal principles.
- Stopping a perchance inappropriate supplier is not nan eventual goal; nan privilege is to thief patients consciousness amended and trim nan consequence of harm.
- Non-drug (behavioral and lifestyle) strategies should often beryllium first line.
- Always activity nan underlying origin of symptoms earlier prescribing.
- Avoiding a risky supplier is important, but objective judgement and individualization stay critical.
- Use nan galore disposable resources for patients, caregivers and clinicians to support implementation and deprescribing.
Balancing real-world practice, investigation gaps and diligent and caregiver needs
The sheet acknowledges that guidelines and systematic reviews often deficiency specificity for nan oldest aliases astir analyzable patients, and that real-life symptoms (e.g., insomnia, involuntary weight loss) are not ever tied to a azygous clear diagnosis. As described successful nan article's discussion, recommendations stay flexible, encouraging clinicians to tailor approaches according to each individual's objective status, functional goals and life circumstances.
"We admit that simply removing a medicine whitethorn not beryllium enough, particularly if symptoms return aliases worsen," said Dr. Campbell. "Our intent is to supply practical, prioritized alternatives that tin beryllium started aliases considered correct away, truthful that attraction is some safer and responsive to what matters astir to older adults and their caregivers. We want clinicians to person existent tools, not conscionable warnings."
Authors are from nan pursuing states: Alabama, Arkansas, California, Colorado, Connecticut, Illinois, Indiana, Iowa, Maine, Michigan, Missouri, New York, Texas and Utah.
Source:
Journal reference:
American Geriatrics Society Beers Criteria® Alternatives Panel., et al. (2025) Alternative Treatments to Selected Medications successful nan 2023 American Geriatrics Society Beers Criteria®. Journal of nan American Geriatrics Society. doi.org/10.1111/jgs.19500