Identifying High Risk "pathogen X" With Potential To Spark Future Pandemics

Announcing a caller article publication for Zoonoses journal. In past decades, galore emerging infectious diseases person markedly affected world wellness and social-economic development.

Consequently, nan conception of "disease X" has been developed and lists of nan pathogens pinch imaginable to origin early pandemics person been projected and updated respective times by nan World Health Organization. This article analyses nan awesome features of pathogens pinch precocious probability to origin early COVID-19-like pandemics, connected nan ground of their transmission routes, animal-human interfaces, herd immunity barriers, and evolutionary and mutational characteristics. High-priority viral infectious diseases pinch imaginable to go illness X successful nan future, are besides evaluated connected nan ground of their transmission pathways, including airborne/respiratory, vector-borne, and nonstop contact. Overall, viruses had overmuch greater likelihood of becoming "pathogen X" than either germs aliases different microorganisms.

Respiratory viruses, peculiarly RNA viruses, person notably precocious imaginable to go pathogen X. Vector-borne viruses mightiness besides go pathogen X, and mosquito-borne viruses would beryllium much apt than tick-borne viruses to do so. Many contagious viral infectious diseases lead to terrible objective outcomes but person comparatively debased likelihood of causing world pandemics. Coronaviruses successful nan Coronaviridae and influenza viruses successful nan Orthomyxoviridae were identified arsenic top-priority pathogens X pinch imaginable to origin nan adjacent COVID pandemic.