How The Latest Frewitt Flexmills Are Crushing The Opposition

Copyright: NürnbergMesse / Thomas Geiger

High-speed and high-precision micro-milling (micronisation) play a important domiciled successful various industries, including pharmaceuticals, nutrient accumulation and nan improvement of captious earthy materials for artillery production. Reducing nan particle size of substances to heighten their properties and functionalities is often a captious measurement successful making powdered products much effective, whether arsenic ingredients for nan latest oncology narcotics aliases diverse, basal materials for making electrical conveyance (EV) batteries.

By achieving particle sizes ranging from azygous digit µm, and up toto 100 µm done micro-milling, and 50 nm to 500 nm done nano-milling, nan aboveground area of particles is importantly increased. This enhancement is peculiarly beneficial successful pharmaceutical applications, wherever it improves properties specified arsenic solubility and bioavailability.

Discover B2B Marketing That Performs

Combine business intelligence and editorial excellence to scope engaged professionals crossed 36 starring media platforms.

Find retired much

Latest instrumentality connected show astatine POWTECH

This September, Frewitt will beryllium demonstrating nan latest innovations successful good micronisation instrumentality from 23-25 September astatine nan POWTECH show successful Nuremberg, Germany. Highlights see nan motorboat of Frewitt’s newest FlexMills – nan PMC-260 and PMC-260 Cryo. Here we person an exclusive first look:

FlexMill PMC-260

The PMC-260 is simply a premium-quality, high-speed pin mill perfect for accumulation applications requiring a precocious output of homogeneous, micronised granular products down to a fineness of 5 µm. FlexMill integrates 2 milling processes into a azygous platform, making nan PMC-260 nan champion solution for combining micronisation and costs saving.

The continuous pin-mill is designed to process batches from 100g to 150 kg/h, while maintaining a compact and modular creation truthful that it is easy to spot successful Laminar Air Flow (LAF) aliases to afloat merge into astir immoderate process flow. Frewitt’s celebrated modularity besides ensures each PMC-160 and PMC-260 processing heads supply nan usability pinch easy handling and cleaning.

Constructed to guarantee optimal, reliable accumulation successful Good Manufacturing Practice (GMP) and precocious containment for a wide scope of products, nan PMC-260 has been designed to guarantee that identical results are guaranteed successful nan scale-up from laboratory to aviator to full-scale business accumulation standard levels.

Process characteristics:

• Size simplification scope 2 mm – 5 µm
• Productivity 2 l/h – 150 l/h
• Temp. scope of merchandise -20°C to +60°C
• Product density up to 2kg / dm³

Suitable for pharmaceutical, battery, chemic and nutrient processing, nan PMC-260 includes arsenic modular an integrated dosing system, integrated cooling strategy and mobile cart pinch lifting device; while options see WIP cleaning, controlled milling nether inverted atmosphere, circumstantial civilization tooling, and unit and somesthesia sensors, among galore different further features.

FlexMill PMC-260 Cryo

The PMC-260 Cryo features nan aforesaid premium-quality, high-speed mill but for accumulation applications requiring a precocious output of homogeneous, micronised granular products down to a fineness of 5 µm. The PMC-260 Cryo besides features 2 milling heads successful 1 system, arsenic good arsenic galore of nan aforesaid modular features, positive integration of nan Cryogenic Feeder CF-25 and options which utilise liquid nitrogen to frost materials to their constituent of brittleness, facilitating powder size reduction. 

Due to its versatility and precocious performance, nan mill tin beryllium utilized successful galore demanding milling processes: achieving optimum particle size distribution; milling temperature-sensitive products; aliases moreover perchance explosive substances.

Process characteristics:

• Size simplification scope 2 mm – 5 µm
• Productivity 2 l/h – 150 l/h
• Temp. scope of merchandise -196°C to +60°C
• Product density up to 2kg / dm³

Featuring easy top-down cleaning, reduced merchandise interaction aboveground areas and reduced power consumption, nan PMC-260 cryo allows users to trim polymer type products to powder and limits nan arena of degradation, hence preserving nan value of nan milled product.

How good micronisation and nano-milling are transforming industry

Pharmaceuticals
Active Pharmaceutical Ingredients (APIs) are a important portion of galore modern narcotics and nano milling is simply a captious method for improving nan bioavailability of water-soluble APIs by reducing nan API successful size to nan nanometre range, typically beneath 200nm, and past stabilising it pinch biocompatible surfactants. Increasing nan aboveground area straight correlates to an summation successful nan dissolution complaint of nan last merchandise and allows for highly concentrated solutions.

Such processes often require a wholly sterile environment, and this is erstwhile having a specialised solution supplier connected committee is key. Frewitt has been a cardinal subordinate successful nan pharmaceutical, battery, nutrient and good chemic industries for complete 75 years and its nano-milling scope contains master features to guarantee nan sterility of pharma products arsenic good arsenic automatic Wash-in-Place and Clean-in-Place (WIP & CIP) systems[i].

Batteries
Homogenous particle size distributions of some anode and cathode materials are captious successful nan artillery market, arsenic particle size distribution (PSD) homogeneity is required to guarantee accordant conductivity from artillery to battery. Stable temperatures are besides required to guarantee nan preservation of nan progressive properties and nan end-users’ expertise to activity pinch nan materials successful consequent down-stream processes.

Food products
Probiotics are gaining fame for their perceived wellness benefits, truthful nan expertise to process dried, concentrated cultures into powders pinch predetermined particle sizes and density is essential. Shelf-life viability is cardinal for producing probiotics successful capable quantities, and to support this, they must beryllium manufactured successful a robust, stable, and somesthesia controlled manner. Additionally, dried, concentrated probiotic cultures are nan astir convenient for incorporating into functional foods.

According to a caller report, functional foods world income are expected to scope US$91.7 cardinal by 2030, truthful nan capacity to mill specified nutrient products is essential[ii]. Frewitt has been processing barren and bedewed milling processes for nan pharmaceutical, good chemic and nutrient sectors since 1946 and offers cutting-edge milling, sieving, homogenising, deagglomerating, conveying, dosing and filling systems for powders, granulates and suspensions[iii].

To study much astir nan latest FlexMill innovations and spot nan FlexMill PMC-260 and FlexMill PMC-260 Cryo successful person, subordinate Frewitt unrecorded astatine nan POWTECH Show Stand 12-566 connected September 23-25, 2025 astatine Messe Nürnberg , Nuremberg, Germany.

[i] https://www.pharmaceutical-technology.com/sponsored/small-matter-big-challenges-nano-milling-in-a-sterilised-environment/
[ii] StrategyR, Probiotics World Market Report. https://www.strategyr.com/market-report-probiotics-forecasts-global-industry-analysts-inc.asp
[iii] https://www.just-food.com/sponsored/functional-foods-milling-dried-probiotics-material-and-cell-culture-media/