New investigation successful Diabetes, Obesity and Metabolism reveals that metformin, a medicine traditionally prescribed to dainty diabetes, is linked to little risks of dementia and early death.
In nan study by investigators astatine Taipei Medical University that included 452,777 adults pinch varying degrees of overweight and obesity, 35,784 cases of dementia and 76,048 deaths occurred complete 10 years. Metformin users exhibited importantly little risks of some dementia and all-cause decease than nonusers.
The benefits of metformin were seen crossed each categories of overweight, obesity, and terrible obesity, pinch 8–12% little risks of dementia and 26–28% little risks of death.
Although our study results are promising for metformin's effects connected dementia and mortality, further investigation is required to research nan mechanisms involved."
Chiehfeng Chen, MD, PhD, MPH, co-corresponding author
Source:
Journal reference:
Lin, Y-L., et al. (2025) Protective Effect of Metformin Against Dementia successful Patients With Obesity: Results From a Global Federated Health Network Analysis. Diabetes, Obesity and Metabolism. doi.org/10.1111/dom.16647.