Combining Tirzepatide And Hormone Therapy Boosts Weight Loss In Postmenopausal Women

5 days ago

Using tirzepatide and menopause hormone therapy astatine nan aforesaid clip leads to accrued weight nonaccomplishment successful postmenopausal women pinch overweight aliases obesity compared to usage of tirzepatide curen alone, according to a study being presented Saturday astatine ENDO 2025, nan Endocrine Society's yearly gathering successful San Francisco, Calif.

These information are nan first to show nan mixed usage of tirzepatide and menopause hormone therapy importantly increases curen effectiveness successful postmenopausal women. Previous studies of nan medicine semaglutide recovered akin results. Achieving these outcomes pinch a 2nd obesity medicine whitethorn bespeak a broader efficacy inclination for pairing these 2 classes of medications."

Regina Castaneda, M.D., investigation chap for nan Division of Endocrinology astatine nan Mayo Clinic successful Jacksonville, Fla.

Menopause-related hormonal changes often consequence successful accrued abdominal fat, decreased musculus wide and altered power expenditure that leads to weight summation and puts millions of women astatine consequence for processing bosom illness and different superior wellness issues.

To corroborate nan presumption that concurrent menopause hormone therapy enhances nan effectiveness of tirzepatide for weight nonaccomplishment successful postmenopausal women, researchers conducted a real-world study utilizing nan physics aesculapian records of 120 postmenopausal women complete a median long of 18 months. The study included 2 cohorts: 40 women utilizing menopause hormone therapy concurrently pinch tirzepatide and 80 women utilizing tirzepatide alone.

The results showed superior full assemblage weight nonaccomplishment percent for women utilizing tirzepatide positive menopause hormone therapy (17%) compared to those utilizing tirzepatide unsocial (14%). In addition, a higher percent of menopause hormone therapy users (45%) besides achieved astatine slightest 20% full assemblage weight loss, compared to 18% of menopause hormone therapy non-users.

"The accusation garnered done this caller study provides important insights to create much effective and personalized weight guidance interventions to trim a postmenopausal woman's consequence of overweight and obesity-related wellness complications," said Maria Daniela Hurtado Andrade, M.D., Ph.D., adjunct professor of medicine and advisor for nan Division of Endocrinology astatine nan Mayo Clinic. "This study underscores nan urgent request for further investigation to amended understand really obesity medications and menopause hormone therapy activity together. Gaining this knowledge could greatly amended nan wellness and well-being of millions of postmenopausal women. It besides points to nan request for amended strategies to make these treatments much accessible and disposable to those who request them."

This investigation was funded by nan National Institutes of Health Bridging Interdisciplinary Careers successful Women's Health Research Grant and nan Mayo Clinic Center for Women's Health Research.

Terms

While we only usage edited and approved contented for Azthena answers, it whitethorn connected occasions supply incorrect responses. Please corroborate immoderate information provided pinch nan related suppliers or authors. We do not supply aesculapian advice, if you hunt for aesculapian accusation you must ever consult a medical master earlier acting connected immoderate accusation provided.

Your questions, but not your email specifications will beryllium shared with OpenAI and retained for 30 days successful accordance pinch their privateness principles.

Please do not inquire questions that usage delicate aliases confidential information.

Read nan afloat Terms & Conditions.