People who are older than 80 should beryllium considered for osteoporosis curen aft a fracture to debar further risk, according to a study being presented Saturday astatine ENDO 2025, nan Endocrine Society's yearly gathering successful San Francisco, Calif.
The load of osteoporosis is rising arsenic nan world organization ages rapidly," said Gianina Flocco, M.D., a resident astatine nan Cleveland Clinic successful Cleveland, Ohio. "Our study supports nan initiation of osteoporosis curen aft a fracture successful group older than 80 years, arsenic it has been shown to alteration some hospitalization and mortality."
Gianina Flocco, M.D., resident astatine nan Cleveland Clinic successful Cleveland, Ohio
Flocco and colleagues utilized nan TriNextX wellness investigation database to study 88,676 patients aged 80 and older who suffered a fracture owed to bony deterioration aliases weakness caused by osteoporosis.
The patients were segmented into 2 groups. The first included 44,338 patients who were treated pinch bisphosphonates, denosumab, raloxifene aliases teriparatide. The 2nd group had nan aforesaid number of patients, but included those who didn't person immoderate osteoporosis treatments.
Patients were followed for 5 years aft nan first fracture. The investigation accounted for comorbidities, including hypertension, diabetes, ischemic bosom disease, obesity, bosom failure, stroke, COPD, chronic kidney disease, hyperlipidemia, rheumatoid arthritis, neoplasm and vitamin D deficiency.
The patients successful nan curen group knowledgeable a little consequence of hospitalization. This group besides knowledgeable little all-cause mortality.
Flocco said that nan load of osteoporosis is expected to summation successful nan future. These study results support their proposal to dainty older patients who are astir susceptible to fractures arsenic they proceed to age.
"The results of our study support nan request to heighten nan individualized initiation of curen of osteoporosis, moreover successful group who are older than 80", she said. "Treating group to trim nan load of osteoporosis complications, for illustration fractures starring to disablement aliases death, would play a important domiciled successful improving wellness span successful nan increasing older population."